Overview

LKM1 test is a blood test that detects the presence of liver-kidney microsomal antibodies in the blood. These antibodies are associated with autoimmune hepatitis and certain liver diseases such as hepatitis C. The test is performed by taking a blood sample from the patient and analyzing it in a laboratory. A positive result indicates the presence of LKM1 antibodies in the blood, which may require further testing and evaluation by a specialist.

Who should do this test?

Patients with suspected autoimmune hepatitis: LKM1 test is primarily done to evaluate autoimmune hepatitis, a liver disease that results from an attack on liver cells by the immune system. The presence of LKM1 antibodies in the blood can help diagnose autoimmune hepatitis, especially in patients who are negative for other markers of the disease.

Patients with suspected drug-induced liver injury: LKM1 test may also be ordered in patients who have been exposed to drugs that are known to cause liver damage. Certain drugs have been linked to the production of LKM1 antibodies, which can lead to liver inflammation and damage.

Patients with unexplained liver dysfunction: LKM1 test may be considered in patients who have elevated liver enzymes but no clear cause of liver dysfunction. The presence of LKM1 antibodies in such patients may indicate an autoimmune response against the liver, leading to liver inflammation and damage.

What to do if the test is abnormal?

Consult with a healthcare provider: If the result of the LKM1 test is abnormal, the first step is to consult with a healthcare provider. They can help interpret the results and determine what further testing or treatment may be necessary.

Follow up with additional testing: Depending on the results of the LKM1 test, additional testing may be necessary to determine the cause of the abnormal results. These tests may include liver function tests, imaging studies, and other blood tests.

Follow recommended treatment plan: If a diagnosis is made based on the LKM1 test results and additional testing, it is important to follow the recommended treatment plan. Treatment may include medications, lifestyle changes, and other interventions to manage the underlying condition and prevent further damage to the liver.

What is the normal range of LKM1-Antibodies to Liver Kidney Microsomes (Qualitative)?

The normal range for adult males is Negative,the normal range for adult females is Negative