Creatinine 8.3 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 8.3 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 8.3 is dangerous, good or bad.
Published Date : 2023-07-14T00:31:57.337Z
Updated Date : 2024-04-11T19:29:34.215+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 8.3 mg/dl mean in men?
What does a creatinine of 8.3 mg/dl mean in women?
Is creatinine 8.3 dangerous?
What is the normal range and is a creatinine of 8.3 mg/dl normal?
What could cause a creatinine level of 8.3?
What other tests should be done if creatinine level is 8.3?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 8.3?
What is my GFR if my creatinine level is 8.3?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that our bodies naturally produce as a result of muscle activity. When our muscles work, they generate something called creatine phosphate, and serum creatinine is like a leftover from this process. It's kind of like when you cook a delicious meal and end up with some scraps or leftovers afterwards. Our bodies produce serum creatinine at a steady pace, meaning that the amount in our blood stays relatively constant over time. However, the level of serum creatinine can vary from person to person, depending on their muscle mass. Generally, men have higher levels of serum creatinine than women because they tend to have more muscle. On the other hand, during pregnancy, the levels of serum creatinine in women tend to be lower. So, think of serum creatinine as a marker that helps us understand how much muscle activity is happening in our bodies. It's like a little clue about how our muscles are doing, and it can differ between individuals based on their gender and whether they are expecting a baby.1
How is creatinine measured?
A serum creatinine lab test is a simple blood test that helps doctors check how well our kidneys are functioning. Before the test, it is important to fast for a few hours, meaning we should not eat or drink anything except water. This helps ensure accurate results. Once at the lab, a trained technician will gently tie a band around our upper arm to make our veins more visible. They will then clean the area with an alcohol swab and insert a small needle to draw a small amount of blood. This may feel like a quick pinch but should not cause much pain. The collected blood sample will then be sent to the lab for analysis. In the lab, the technicians will use a machine to measure the concentration of creatinine in our blood. Creatinine is a waste product produced by our muscles and eliminated by our kidneys. By measuring its level, the doctors can assess how well our kidneys are filtering out this waste. After the lab test, the results will be sent to our doctor who will then discuss the findings with us and provide any necessary recommendations or treatments based on the results.
What does a creatinine of 8.3 mg/dl mean in men?
The normal range for creatinine in women is between 0.73 and 1.18. If your creatinine level is 8.3 mg/dl, it is very dangerous and could be life-threatening. It is highly recommended that you go to the hospital right away for immediate medical attention. Do not try to treat yourself at home.3,4
What does a creatinine of 8.3 mg/dl mean in women?
The normal range for creatinine in women is between 0.55 and 1.02. If your creatinine level is 8.3 mg/dl, it is considered life-threatening. It is strongly recommended that you go to the hospital right away, as you may require immediate admission and potentially dialysis. Please do not try to treat yourself and seek medical help immediately.3,4
Is creatinine 8.3 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 8.3 in male across different ages
| Age Group | Is Creatinne of 8.3 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 8.3 in female across different ages
| Age Group | Is Creatinne of 8.3 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 8.3 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 8.3 is considered abnormal.
What could cause a creatinine level of 8.3?
- Acute kidney injury: This is a sudden loss of kidney function that can be caused by various factors such as dehydration, severe infection, or medication toxicity.
- Chronic kidney disease: This refers to the long-term damage to the kidneys, often caused by conditions like diabetes, high blood pressure, or glomerulonephritis.
- Urinary tract obstruction: Blockage in the urinary tract can prevent the normal flow of urine, leading to increased creatinine levels. This can be caused by kidney stones, tumors, or enlarged prostate.
- Severe dehydration: When the body lacks enough fluid, the kidneys may struggle to filter waste products effectively, resulting in elevated creatinine levels.
- Rhabdomyolysis: This condition occurs when muscle tissue breaks down rapidly, releasing myoglobin into the bloodstream. The breakdown products can overload the kidneys and raise creatinine levels.
- Pyelonephritis: This is a severe kidney infection that can cause inflammation and damage to the kidneys, leading to impaired kidney function and increased creatinine levels.
- Glomerulonephritis: Inflammation of the glomeruli, the tiny filters in the kidneys, can impair their ability to filter waste products properly, resulting in elevated creatinine.
- Nephrotic syndrome: This condition is characterized by increased levels of protein in the urine and low levels of protein in the blood. It can cause damage to the kidneys and lead to elevated creatinine levels.
- Medication side effects: Certain medications, such as some antibiotics, antifungal drugs, and nonsteroidal anti-inflammatory drugs (NSAIDs), can cause kidney damage and result in increased creatinine levels.
- Hemolytic uremic syndrome: This rare condition involves the destruction of red blood cells, which can clog the tiny blood vessels in the kidneys and impair their function, leading to elevated creatinine levels.
What other tests should be done if creatinine level is 8.3?
Serum Electrolytes
The Serum Electrolytes test is important in this case because it helps evaluate the balance of important minerals like sodium, potassium, and chloride in the blood. Abnormal levels of these electrolytes can indicate kidney dysfunction, which could be a possible cause of the high creatinine level. Monitoring electrolyte levels can provide additional information about the overall kidney function and guide treatment decisions.
Blood Urea
The Blood Urea test is important because it measures the amount of urea nitrogen in the blood, which helps assess kidney function. In this case, a creatinine level of 8.3 mg/dl suggests severe kidney impairment, and the Blood Urea test can provide additional information on the overall kidney function and the body's ability to eliminate waste products. Monitoring blood urea levels can aid in diagnosing and managing kidney diseases.
Estimated GFR
The Estimated GFR (glomerular filtration rate) test is crucial in assessing kidney function. With a creatinine level of 8.3 mg/dl, it indicates severe impairment of kidney function. The Estimated GFR test helps determine the degree of kidney damage and guides treatment decisions, such as medication dosages or the need for dialysis.
HBA1C
The HBA1C test is important in this scenario as it helps in monitoring long-term blood sugar levels and assessing the effectiveness of diabetes management. Since a high creatinine level indicates kidney dysfunction, it is crucial to ensure blood sugar levels are well-controlled to prevent further kidney damage. The HBA1C test provides valuable information to guide treatment decisions and prevent complications in individuals with diabetes and kidney dysfunction.
LDH
The LDH test is important in this case because it helps to differentiate between various causes of elevated creatinine levels, such as muscle breakdown or kidney damage. LDH levels can help determine if the elevated creatinine is due to muscle-related issues or kidney dysfunction, guiding further diagnostic and treatment decisions. Additionally, LDH levels can also provide information on the severity and prognosis of kidney disease.
Random Sugar
The Random Sugar test is important because it helps evaluate blood glucose levels at any given time, providing valuable information about the patient's current blood sugar control. In the case of a creatinine level of 8.3 mg/dl, a Random Sugar test can help determine if the elevated creatinine is due to uncontrolled diabetes, as high blood sugar levels can lead to kidney damage. This test can guide healthcare professionals in managing the patient's diabetes and preventing further complications.
What is the relation between creatinine and kidney function?
Creatinine, a substance synthesized by the body at a steady pace, gets completely sieved out by the kidney into the urine. In the event of kidney dysfunction caused by various factors, the levels of creatinine surge. Consequently, creatinine emerges as a highly valuable means of assessing kidney performance.
Why do doctors ask for GFR if my creatinine level is 8.3?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 8.3?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 8.3
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 8.46 mL/min/1.73 m2 Female : 6.28 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 8.37 mL/min/1.73 m2 Female : 6.21 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 8.29 mL/min/1.73 m2 Female : 6.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 8.2 mL/min/1.73 m2 Female : 6.09 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 8.13 mL/min/1.73 m2 Female : 6.03 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 8.05 mL/min/1.73 m2 Female : 5.98 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 7.98 mL/min/1.73 m2 Female : 5.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 7.92 mL/min/1.73 m2 Female : 5.88 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 7.86 mL/min/1.73 m2 Female : 5.83 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 7.8 mL/min/1.73 m2 Female : 5.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 7.74 mL/min/1.73 m2 Female : 5.74 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 7.68 mL/min/1.73 m2 Female : 5.7 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 7.63 mL/min/1.73 m2 Female : 5.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 7.58 mL/min/1.73 m2 Female : 5.62 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 7.53 mL/min/1.73 m2 Female : 5.59 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 7.48 mL/min/1.73 m2 Female : 5.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 7.44 mL/min/1.73 m2 Female : 5.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 7.4 mL/min/1.73 m2 Female : 5.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 7.35 mL/min/1.73 m2 Female : 5.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 7.31 mL/min/1.73 m2 Female : 5.43 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 7.27 mL/min/1.73 m2 Female : 5.4 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 7.23 mL/min/1.73 m2 Female : 5.37 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 7.2 mL/min/1.73 m2 Female : 5.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 7.16 mL/min/1.73 m2 Female : 5.31 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 7.13 mL/min/1.73 m2 Female : 5.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 7.09 mL/min/1.73 m2 Female : 5.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 7.06 mL/min/1.73 m2 Female : 5.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 7.03 mL/min/1.73 m2 Female : 5.21 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 7.0 mL/min/1.73 m2 Female : 5.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 6.97 mL/min/1.73 m2 Female : 5.17 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 6.94 mL/min/1.73 m2 Female : 5.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 6.91 mL/min/1.73 m2 Female : 5.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 6.88 mL/min/1.73 m2 Female : 5.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 6.85 mL/min/1.73 m2 Female : 5.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 6.82 mL/min/1.73 m2 Female : 5.06 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 6.8 mL/min/1.73 m2 Female : 5.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 6.77 mL/min/1.73 m2 Female : 5.03 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 6.75 mL/min/1.73 m2 Female : 5.01 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 6.72 mL/min/1.73 m2 Female : 4.99 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 6.7 mL/min/1.73 m2 Female : 4.97 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 6.67 mL/min/1.73 m2 Female : 4.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 6.65 mL/min/1.73 m2 Female : 4.94 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 6.63 mL/min/1.73 m2 Female : 4.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 6.61 mL/min/1.73 m2 Female : 4.9 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 6.59 mL/min/1.73 m2 Female : 4.89 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 6.56 mL/min/1.73 m2 Female : 4.87 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 6.54 mL/min/1.73 m2 Female : 4.85 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 6.52 mL/min/1.73 m2 Female : 4.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 6.5 mL/min/1.73 m2 Female : 4.82 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 6.48 mL/min/1.73 m2 Female : 4.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 6.46 mL/min/1.73 m2 Female : 4.8 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 6.44 mL/min/1.73 m2 Female : 4.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 6.42 mL/min/1.73 m2 Female : 4.77 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 6.41 mL/min/1.73 m2 Female : 4.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 6.39 mL/min/1.73 m2 Female : 4.74 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 6.37 mL/min/1.73 m2 Female : 4.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 6.35 mL/min/1.73 m2 Female : 4.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 6.34 mL/min/1.73 m2 Female : 4.7 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 6.32 mL/min/1.73 m2 Female : 4.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 6.3 mL/min/1.73 m2 Female : 4.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 6.29 mL/min/1.73 m2 Female : 4.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 6.27 mL/min/1.73 m2 Female : 4.65 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 6.25 mL/min/1.73 m2 Female : 4.64 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 6.24 mL/min/1.73 m2 Female : 4.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 6.22 mL/min/1.73 m2 Female : 4.62 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 6.21 mL/min/1.73 m2 Female : 4.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 6.19 mL/min/1.73 m2 Female : 4.59 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 6.18 mL/min/1.73 m2 Female : 4.58 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 6.16 mL/min/1.73 m2 Female : 4.57 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 6.15 mL/min/1.73 m2 Female : 4.56 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 6.13 mL/min/1.73 m2 Female : 4.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 6.12 mL/min/1.73 m2 Female : 4.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 6.11 mL/min/1.73 m2 Female : 4.53 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 6.09 mL/min/1.73 m2 Female : 4.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 6.08 mL/min/1.73 m2 Female : 4.51 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 6.06 mL/min/1.73 m2 Female : 4.5 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 6.05 mL/min/1.73 m2 Female : 4.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 6.04 mL/min/1.73 m2 Female : 4.48 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 8.3
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
