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Triple Marker Test in Pune: Price, Symptoms, Normal Range

Triple Marker Test in Pune

Price, Symptoms, Normal Range

Triple Marker Test is a blood test that checks for three substances to detect the risk of birth defects in the fetus. It costs Rs.2900.0 .

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Updated At : 2023-11-11T19:24:52.446+05:30

3 Key Points

  • Why is prenatal testing or pregnancy screening done?

  • Prenatal screening is an essential component of prenatal care, encompassing a series of tests and procedures conducted during both the first and second trimesters of pregnancy to assess the health of the expectant mother and the developing fetus.
  • n the first trimester, common tests include the nuchal translucency ultrasound, which measures the fluid at the back of the baby's neck, and the blood test that analyzes pregnancy-associated plasma protein-A (PAPP-A) and human chorionic gonadotropin (hCG) levels. These tests aim to screen for chromosomal abnormalities such as Down syndrome and trisomy 18.
  • Moving into the second trimester, prenatal screening involves the Triple Marker Test, which examines maternal blood for alpha-fetoprotein (AFP), hCG, and unconjugated estriol levels. Additionally, an ultrasound known as the anatomy scan or anomaly scan is performed to evaluate the baby's physical development and screen for structural abnormalities.
  • What diseases in the baby can be detected by the Triple Marker Test?

  • The Triple Marker Test, also known as the Triple Test or the Multiple Marker Screening, is a prenatal screening procedure that aims to assess the risk of specific fetal abnormalities.
  • Down Syndrome: This genetic condition is caused by an extra copy of chromosome 21, resulting in intellectual disabilities, distinct facial features, and potential health complications. The Triple Marker Test measures levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) in the mother's blood to help identify pregnancies at increased risk of Down syndrome.
  • Trisomy 18 (Edwards Syndrome): Trisomy 18 is a chromosomal disorder characterized by the presence of an extra copy of chromosome 18. Babies with this condition often have severe developmental delays, heart defects, and other organ abnormalities. The Triple Marker Test can help detect pregnancies with an elevated risk of Trisomy 18 by assessing the levels of AFP, hCG, and uE3 in the maternal blood.
  • The Triple marker test only provides an estimation of the risk of these diseases. Further investigation is needed if the risk score is high. The test is not confirmatory.
  • When should the triple marker test be done?

  • The right timing or period for the triple marker test is the second trimester.
  • The second trimester starts at the beginning of the 4th month of the pregnancy, and ends at the end of the 6th month of gestation.
  • Triple marker test is usually recommended between 15-20 weeks of gestation.

What is Triple Marker Test

The Triple Marker Test is a prenatal screening test that measures the levels of three substances in a pregnant womans blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and estriol. The test is usually done between the 15th and 20th week of pregnancy. It helps to identify if the baby is at risk of certain birth defects or genetic disorders such as Down syndrome. The test involves a simple blood draw from the mother and the results are usually available within a few days.

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Do I need this test?

Let's find out whether you need the Triple Marker Test test. Answer the following 5 questions and get a free instant result!

Have you experienced any unusual fatigue or exhaustion in the last few weeks
Have you experienced any unusual fatigue or exhaustion in the last few weeks

Have you experienced any unusual swelling of your hands or feet
Have you experienced any unusual swelling of your hands or feet

Have you noticed any unusual fluid retention
Have you noticed any unusual fluid retention

Have you had any changes in your appetite
Have you had any changes in your appetite

Have you experienced any other unusual symptoms or discomfort
Have you experienced any other unusual symptoms or discomfort

Result :

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Which symptoms are related to Triple Marker Test?

If you have Possible Symptoms,Abnormal Fatigue,Nausea,Abdominal Cramps,Unexplained Weight Gain, you may need to get tested.

Here is the complete list of symptoms

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Who should do this test?

Pregnant women over the age of 35,Women with a family history of chromosomal abnormalities,Women with a previous pregnancy affected by chromosomal abnormalities should do this test

  • Pregnant women over the age of 35: Women over the age of 35 are at a higher risk of having a baby with chromosomal abnormalities, such as Down syndrome. Therefore, the triple marker test is recommended for this age group.
  • Women with a family history of chromosomal abnormalities: If a woman has a family history of chromosomal abnormalities, she may be at a higher risk of having a baby with a similar condition. In such cases, the triple marker test can help detect any potential issues.
  • Women with a previous pregnancy affected by chromosomal abnormalities: If a woman has had a previous pregnancy affected by chromosomal abnormalities, she may be advised to undergo the triple marker test during subsequent pregnancies to assess the risk of a similar condition.

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What to do if the test is abnormal?

  • First and foremost, the person should not panic or assume the worst. An abnormal result on a triple marker test does not necessarily mean that there is something wrong with the pregnancy, but it does warrant further investigation and monitoring.
  • The person should speak with their healthcare provider as soon as possible to discuss the results and any necessary next steps. Depending on the specific abnormality found, the healthcare provider may recommend additional testing or monitoring, such as a detailed ultrasound or amniocentesis.
  • It is important for the person to follow the healthcare providers recommendations and to continue to attend all scheduled prenatal appointments. By staying informed and working closely with their healthcare team, the person can ensure that they are receiving the best possible care for themselves and their developing baby.

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In which diseases is Triple Marker Test abnormal?

Neural tube defects
Chromosomal abnormalities
Multiple pregnancies
Hypothyroidism
Anemia
Rh incompatibility
Infectious diseases

Triple Marker Test Normal Range - Age Wise

Triple Marker Test Normal Ranges in Males | Triple Marker Test Normal Ranges in Men
Age Range
>= 0 years *

Triple Marker Test Normal Ranges in Females | Triple Marker Test Normal Ranges in Women
Age Range
>= 0 years *

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Interpretation

What are the normal values for AFP, Uconjugated Estriol and Beta Hcg for different weeks of gestation?

Weeks of Gestation AFP Levels Uconjugated Estriol Values Beta HCG Values
14 25.5 3.44 18.1
15 27.7 4.11 15.2
16 30.9 4.95 12.1
17 34.6 5.87 10.2
18 38.55 6.67 8.45
19 42.7 7.63 7.39

References
: Kaur G, Srivastav J, Sharma S, Huria A, Goel P, Chavan BS. Maternal serum median levels of alpha-foetoprotein, human chorionic gonadotropin & unconjugated estriol in second trimester in pregnant women from north-west India. Indian J Med Res. 2013;138(1):83-8. PMID: 24056560; PMCID: PMC3767258.

What are the normal risk evaluation cut-offs for detecting different diseases based on the results of the Triple Marker Test

The normal risk cutoffs for various genetic disorders based on the Triple Marker Test are as follows:

Condition Risk
Downs Syndrome 1:270
Edwards Syndrome 1:350
Neural Tube Defects AFP > 2.5 MoM
Reference: Chen, Y., Wang, X., Li, L. et al. New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age. BMC Pregnancy Childbirth 20, 776 (2020). https://doi.org/10.1186/s12884-020-03464-z

Treatment options

Currently no treatment options details are avaialble for this report,check back later or consult your doctor

Technical information

Parameter Details
LOINC Codes 11579-0
Sample Type Required serum
Principle of Measurement CMIA / CLIA / EIA
Units of Measurement -
Triple Marker Test Cost in Pune

What is the Cost of Triple Marker Test?

The test costs Rs.2900.0

Details about cost price of Triple Marker Test

  • Free home visit for sample collection for Triple Marker Test in all parts of Pune City is included in the cost price.
  • Kindly note that we do not charge any visit charges as most other labs. This is because the cost of Triple Marker Test in Pune is already high and we do not wish to levy additional charges on patients.
  • The cost price of Triple Marker Test is updated only in case of sudden changes in government rules. You are requested to check the latest cost price of Triple Marker Test as charged by Pathofast on this page.
  • All online forms of payment are available at our lab, including Gpay, Payumoney, credit and debit card as well as cheque payment.

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How to book Triple Marker Test in Pune?

Book a free home visit in Pune online, call our lab at 020 49304930 or get in touch using Watsapp.

Pathofast offers Triple Marker Test at our center in Manisha Terrace, Moledina Road, Pune, Camp, India
Our diagnostic center in Pune and pathology lab in Pune, is known for its exceptional hygiene, polite staff and quick reports
Our Pune Center, is located close to the railway station and the Swargate Central Bus Depot, as well as the new Metro Lines
Please choose an option below to proceed with your booking:

Near which locations or areas of Pune is Triple Marker Test available?

Pathofast offers lab test service for Triple Marker Test near : Camp, Koregaon Park, Kalyani Nagar, Viman Nagar, Aundh, Baner, FC Road, Tilak Road, Ravet, Aundh, Pimpri Chinchwad, Nagar Road, Dhole Patil Road.

What are the Advantages of choosing a lab near you for blood test services?
  • Choosing a nearby lab reduces the time it takes for the sample to be transported
  • This leads to reduced sample deterioration.
  • While most patients are unaware, blood samples must be transported under strictly controlled temperature, and choosing a lab near you makes this easier to achieve.
  • Even if the lab does not adhere to temperature control, the time spent between sample collection and analysis reduces and this is more likely to produce more accurate results

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Dr.Bhargav Raut - Profile Image

Reviewed By -

Dr.Bhargav Raut is a qualified Pathologist, with over 5 years of experience in the field
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