Overview

Dexamethasone suppression test is a medical test used to diagnose Cushings syndrome. It involves administering a dose of dexamethasone, a synthetic steroid, to a patient and measuring their cortisol levels before and after. The test is typically performed overnight, with blood samples drawn in the morning. The results are used to determine if the patients cortisol levels are suppressed, indicating a normal response, or elevated, indicating Cushings syndrome.

Who should do this test?

Patients with suspected Cushings syndrome: Dexamethasone Suppression Test is commonly used to diagnose or rule out Cushings syndrome, a condition characterized by high levels of cortisol hormone in the body. This test helps to differentiate between the various types of Cushings syndrome and other conditions that mimic its symptoms.

Patients with suspected adrenal gland disorders: Dexamethasone Suppression Test may also be used to diagnose and monitor the treatment of certain adrenal gland disorders, such as adrenal carcinoma and adrenal adenoma.

Patients with unexplained depression or anxiety: In some cases, dexamethasone suppression test may be used to diagnose depression or anxiety disorders that are resistant to treatment. Elevated cortisol levels have been associated with these conditions, and the test can help to identify the underlying cause.

What to do if the test is abnormal?

First, the individual should consult their physician or endocrinologist to discuss the results of their Dexamethasone Suppression Test. The physician will be able to explain the significance of the abnormal results and what further testing or treatment may be necessary.

Depending on the specific results of the test, further diagnostic testing may be recommended to determine the underlying cause of the abnormal results. This may include additional hormone testing, imaging studies such as a CT scan or MRI, or referral to a specialist such as an endocrinologist.

Treatment options for abnormal Dexamethasone Suppression Test results will depend on the underlying cause of the abnormality. In some cases, medication may be prescribed to help regulate hormone levels, while in other cases surgery may be necessary to remove a tumor or other abnormal growth. The physician will work with the patient to develop an appropriate treatment plan based on their individual needs and circumstances.

What is the normal range of Dexamethasone Suppression test (DST) for ACTH (2 samples)?

The normal range for adult males is Not DefinedThe normal range for adult females is Not Defined.