Creatinine 8.0 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 8.0 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 8.0 is dangerous, good or bad.
Published Date : 2023-07-14T00:31:57.337Z
Updated Date : 2024-04-11T19:29:34.120+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 8.0 mg/dl mean in men?
What does a creatinine of 8.0 mg/dl mean in women?
Is creatinine 8.0 dangerous?
What is the normal range and is a creatinine of 8.0 mg/dl normal?
What could cause a creatinine level of 8.0?
What other tests should be done if creatinine level is 8.0?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 8.0?
What is my GFR if my creatinine level is 8.0?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that is naturally made in our bodies as a result of a chemical called creatine phosphate found in our muscles. It is produced constantly, without stopping. The amount of serum creatinine present in our blood depends on the size of our muscles, with men generally having more than women. Interestingly, during pregnancy, the level of serum creatinine tends to be lower. So, think of serum creatinine as a natural byproduct that tells us a bit about our muscle mass and can vary depending on our gender and whether we are expecting a baby.1
How is creatinine measured?
A serum creatinine lab test is a simple blood test that helps measure the level of creatinine in our bodies. Before the test, it is important to follow some pretest preparations. These may include avoiding certain medications or supplements, fasting for a few hours, and drinking plenty of water to stay hydrated. Once in the lab, a healthcare professional will draw a small amount of blood from a vein in our arm using a needle. Don't worry, it might feel like a quick pinch but it's usually not too painful. The blood sample will then be sent to a special machine called a spectrophotometer, which will measure the amount of creatinine present. The spectrophotometer uses light to determine the concentration of creatinine in the blood. It does this by measuring how much light is absorbed or reflected by the blood sample. The results of the test will help doctors assess kidney function and determine if there are any potential issues that need to be addressed.
What does a creatinine of 8.0 mg/dl mean in men?
The normal range for creatinine in women is between 0.73 and 1.18. If your creatinine value is 8.0 mg/dl, it is considered very dangerous. It is strongly recommended that you go to the hospital right away and you may need dialysis treatment. Do not try to treat yourself, seek medical help immediately.3,4
What does a creatinine of 8.0 mg/dl mean in women?
A normal creatinine level for women is between 0.55 and 1.02. If your creatinine level is 8.0 mg/dl, it is considered very dangerous. It is important that you go to the hospital right away and you may need dialysis treatment. Please do not try to treat yourself.3,4
Is creatinine 8.0 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 8.0 in male across different ages
| Age Group | Is Creatinne of 8.0 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 8.0 in female across different ages
| Age Group | Is Creatinne of 8.0 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 8.0 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 8.0 is considered abnormal.
What could cause a creatinine level of 8.0?
- Chronic kidney disease: A common cause of elevated creatinine levels, indicating impaired kidney function.
- Acute kidney injury: Sudden kidney damage due to various factors such as infections, medications, or decreased blood flow.
- Dehydration: Insufficient fluid intake or excessive fluid loss can lead to elevated creatinine levels.
- Urinary tract obstruction: Blockage in the urinary tract can hinder the normal excretion of creatinine, causing its accumulation.
- Rhabdomyolysis: Severe muscle injury or breakdown can release large amounts of creatinine into the bloodstream.
- High protein diet: Consuming excessive amounts of protein can raise creatinine levels temporarily.
- Certain medications: Some drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics, can affect kidney function and increase creatinine levels.
- Glomerulonephritis: Inflammation of the kidney's filtering units (glomeruli) can impair their function, leading to elevated creatinine levels.
- Polycystic kidney disease: Inherited condition causing the growth of cysts in the kidneys, which can interfere with kidney function.
- Hypothyroidism: Underactive thyroid gland can contribute to kidney dysfunction and elevated creatinine levels.
What other tests should be done if creatinine level is 8.0?
Serum Electrolytes
The Serum Electrolytes test is important for evaluating the balance of essential ions in the body, such as sodium, potassium, and chloride. Abnormalities in electrolyte levels can have significant implications for kidney function, cardiovascular health, and overall body homeostasis. Monitoring electrolytes is crucial in managing patients with high creatinine levels, as it helps identify potential complications and guide appropriate treatment interventions.
Blood Urea
The blood urea test is important because it helps evaluate kidney function. Creatinine is a waste product produced by muscles that is filtered out of the blood by the kidneys. A high creatinine level indicates impaired kidney function, and the blood urea test can further assess kidney health by measuring the amount of urea, another waste product eliminated by the kidneys.
Estimated GFR
The Estimated GFR (glomerular filtration rate) test is important for assessing kidney function in individuals with a creatinine level of 8.0 mg/dl because it provides an estimation of how well the kidneys are filtering waste products from the blood. A GFR below normal range indicates severe kidney damage or dysfunction, which may require immediate medical attention and appropriate treatment. Monitoring GFR levels helps healthcare professionals evaluate kidney health, determine appropriate interventions, and track the progression of kidney disease.
HBA1C
The HbA1c test is important in this case because it measures the average blood sugar level over the past 2-3 months, providing valuable information about long-term glucose control. High creatinine levels can indicate kidney dysfunction, which can affect the accuracy of traditional glucose tests. Therefore, the HbA1c test can be crucial for monitoring and managing diabetes in individuals with elevated creatinine levels.
LDH
The LDH (lactate dehydrogenase) test is important in the context of a creatinine level of 8.0 mg/dl because it helps determine the underlying cause of kidney dysfunction. Elevated LDH levels can indicate kidney damage, such as acute tubular necrosis or glomerulonephritis, which may require immediate medical intervention. Therefore, the LDH test is crucial in assessing the severity and guiding appropriate treatment for individuals with high creatinine levels.
Random Sugar
The Random Sugar test is important in this case as it helps evaluate the blood glucose level at any given time, which is crucial for diagnosing and monitoring diabetes. High creatinine levels can indicate kidney dysfunction, and uncontrolled diabetes can contribute to kidney damage. Therefore, the Random Sugar test can provide valuable information for managing and preventing further complications in patients with elevated creatinine levels.
What is the relation between creatinine and kidney function?
Creatinine, a chemical synthesized within the body at a consistent pace, undergoes complete filtration in the urine by the kidney. In the event of kidney dysfunction caused by various factors, the levels of creatinine experience an elevation. Hence, measuring creatinine serves as a highly valuable means to assess the efficiency of renal function.
Why do doctors ask for GFR if my creatinine level is 8.0?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 8.0?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 8.0
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 8.83 mL/min/1.73 m2 Female : 6.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 8.74 mL/min/1.73 m2 Female : 6.48 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 8.64 mL/min/1.73 m2 Female : 6.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 8.56 mL/min/1.73 m2 Female : 6.35 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 8.48 mL/min/1.73 m2 Female : 6.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 8.4 mL/min/1.73 m2 Female : 6.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 8.33 mL/min/1.73 m2 Female : 6.18 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 8.26 mL/min/1.73 m2 Female : 6.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 8.2 mL/min/1.73 m2 Female : 6.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 8.13 mL/min/1.73 m2 Female : 6.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 8.07 mL/min/1.73 m2 Female : 5.99 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 8.02 mL/min/1.73 m2 Female : 5.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 7.96 mL/min/1.73 m2 Female : 5.91 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 7.91 mL/min/1.73 m2 Female : 5.87 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 7.86 mL/min/1.73 m2 Female : 5.83 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 7.81 mL/min/1.73 m2 Female : 5.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 7.76 mL/min/1.73 m2 Female : 5.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 7.72 mL/min/1.73 m2 Female : 5.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 7.67 mL/min/1.73 m2 Female : 5.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 7.63 mL/min/1.73 m2 Female : 5.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 7.59 mL/min/1.73 m2 Female : 5.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 7.55 mL/min/1.73 m2 Female : 5.6 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 7.51 mL/min/1.73 m2 Female : 5.57 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 7.47 mL/min/1.73 m2 Female : 5.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 7.44 mL/min/1.73 m2 Female : 5.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 7.4 mL/min/1.73 m2 Female : 5.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 7.37 mL/min/1.73 m2 Female : 5.47 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 7.33 mL/min/1.73 m2 Female : 5.44 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 7.3 mL/min/1.73 m2 Female : 5.42 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 7.27 mL/min/1.73 m2 Female : 5.39 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 7.24 mL/min/1.73 m2 Female : 5.37 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 7.21 mL/min/1.73 m2 Female : 5.35 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 7.18 mL/min/1.73 m2 Female : 5.33 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 7.15 mL/min/1.73 m2 Female : 5.3 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 7.12 mL/min/1.73 m2 Female : 5.28 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 7.09 mL/min/1.73 m2 Female : 5.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 7.07 mL/min/1.73 m2 Female : 5.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 7.04 mL/min/1.73 m2 Female : 5.22 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 7.01 mL/min/1.73 m2 Female : 5.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 6.99 mL/min/1.73 m2 Female : 5.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 6.96 mL/min/1.73 m2 Female : 5.17 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 6.94 mL/min/1.73 m2 Female : 5.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 6.92 mL/min/1.73 m2 Female : 5.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 6.89 mL/min/1.73 m2 Female : 5.12 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 6.87 mL/min/1.73 m2 Female : 5.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 6.85 mL/min/1.73 m2 Female : 5.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 6.83 mL/min/1.73 m2 Female : 5.07 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 6.81 mL/min/1.73 m2 Female : 5.05 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 6.78 mL/min/1.73 m2 Female : 5.03 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 6.76 mL/min/1.73 m2 Female : 5.02 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 6.74 mL/min/1.73 m2 Female : 5.0 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 6.72 mL/min/1.73 m2 Female : 4.99 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 6.7 mL/min/1.73 m2 Female : 4.97 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 6.68 mL/min/1.73 m2 Female : 4.96 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 6.67 mL/min/1.73 m2 Female : 4.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 6.65 mL/min/1.73 m2 Female : 4.93 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 6.63 mL/min/1.73 m2 Female : 4.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 6.61 mL/min/1.73 m2 Female : 4.9 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 6.59 mL/min/1.73 m2 Female : 4.89 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 6.58 mL/min/1.73 m2 Female : 4.88 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 6.56 mL/min/1.73 m2 Female : 4.87 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 6.54 mL/min/1.73 m2 Female : 4.85 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 6.52 mL/min/1.73 m2 Female : 4.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 6.51 mL/min/1.73 m2 Female : 4.83 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 6.49 mL/min/1.73 m2 Female : 4.82 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 6.48 mL/min/1.73 m2 Female : 4.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 6.46 mL/min/1.73 m2 Female : 4.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 6.44 mL/min/1.73 m2 Female : 4.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 6.43 mL/min/1.73 m2 Female : 4.77 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 6.41 mL/min/1.73 m2 Female : 4.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 6.4 mL/min/1.73 m2 Female : 4.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 6.38 mL/min/1.73 m2 Female : 4.74 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 6.37 mL/min/1.73 m2 Female : 4.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 6.36 mL/min/1.73 m2 Female : 4.72 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 6.34 mL/min/1.73 m2 Female : 4.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 6.33 mL/min/1.73 m2 Female : 4.7 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 6.31 mL/min/1.73 m2 Female : 4.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 6.3 mL/min/1.73 m2 Female : 4.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 8.0
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
